| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9268438 | Journal of Clinical Virology | 2005 | 6 Pages |
Abstract
The PCR-based methods were more effective in the first few days of infection, whereas the MAC-ELISA became more sensitive 5 or 6 days after disease onset. These results suggest that the best method for dengue diagnosis is a combination of PCR-based and immunological tests. Real-time RT-PCR was more sensitive than the nested RT-PCR approach. Furthermore, it was rapid, reproducible and highly specific, making it a potential method for the diagnosis of dengue fever.
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Authors
Celina de Oliveira Poersch, Daniela Parada Pavoni, Mario H. Queiroz, Luana de Borba, Samuel Goldenberg, Claudia Nunes Duarte dos Santos, Marco Aurélio Krieger,