Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9268442 | Journal of Clinical Virology | 2005 | 6 Pages |
Abstract
The presented in vitro transcription/translation system represents a novel approach for HIV PR expression starting from molecular clones or patient samples. Coupled with the enzyme-kinetic PR assay recently developed in our group it allows to sensitively quantify resistance to PIs. The test system is significantly less laborious and faster than currently available phenotypic drug resistance assays.
Keywords
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Authors
Dieter Hoffmann, Bernd Buchberger, Cordula Nemetz,