Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9276038 | Clinical Microbiology and Infection | 2005 | 5 Pages |
Abstract
Human papilloma virus type 5 (HPV-5) has been associated closely with psoriatic skin in Polish patients, while findings from other countries have indicated a more limited prevalence. The results of the present study, in which a type-specific nested PCR was used, indicated that scales of plaque-type psoriatic skin from 54 Italian patients had a high prevalence (74.1%) of HPV-5 DNA in lesional areas, and a reduced prevalence (33.3%) in non-lesional skin (33.3%), compared to 0% of 20 healthy subjects and 3.6% in the lesional areas of 28 patients with various other dermatological diseases. Individuals negative for HPV-5 DNA had a less severe disease. No correlation was found between the presence of HPV DNA and a patient's age or sex. The data demonstrated a statistically significant association between psoriasis and HPV-5, although results in other geographical areas suggest variable virus spread or ethnic variation in virus colonisation.
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Authors
G. Prignano, C. Ferraro, A. Mussi, F. Stivali, E. Trento, V. Bordignon, E. Crescimbeni, G. Salvati, A.M. Degener, F. Ameglio,