Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9341903 | Experimental Eye Research | 2005 | 9 Pages |
Abstract
The binding capacity of α-crystallin to lens lipids, measured in vitro, increases with age and decreases in diabetic donors that were treated with insulin. Our data support the idea that with age and perhaps certain types of diabetes, more α-crystallin is bound to the membrane and serves as a condensation point to which other crystallins bind and then become oxidized.
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Authors
Vahid Grami, Yernan Marrero, Li Huang, Daxin Tang, Marta C. Yappert, Douglas Borchman,