| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9603193 | Journal of Bioscience and Bioengineering | 2005 | 4 Pages |
Abstract
The effect of glycosaminoglycan addition on a three-dimensional (3D) culture of porcine chondrocyte cells was investigated with a view to use in cartilage regenerative medicine. Chondroitin sulfate C increased the mRNA expression of type 2 collagen, while chondroitin sulfate A did not. Hyaluronic acid of high molecular weight markedly decreased the mRNA expression of both aggrecan and type 2 collagen, although hyaluronic acid of low molecular weight showed no apparent effect.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Shohei Nishimoto, Mutsumi Takagi, Shigeyuki Wakitani, Takuya Nihira, Toshiomi Yoshida,