Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9646425 | Schizophrenia Research | 2005 | 7 Pages |
Abstract
We found that a family history of schizophrenia was not associated with a greater degree of structural brain abnormalities in an ultra-high-risk group, and in fact it was those UHR patients without such history who displayed greater abnormalities, although this only reached significance for the left hippocampus. Thus, it appears that the mechanisms that result in gross morphological anomalies in the hippocampus and anterior cingulate in psychosis are driven more by environmental than genetic factors.
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Authors
Stephen J. Wood, Murat Yücel, Dennis Velakoulis, Lisa J. Phillips, Alison R. Yung, Warrick Brewer, Patrick D. McGorry, Christos Pantelis,