Thermodynamical aspects regarding the formation of self-assembly decylpolyglucoside structures

In this study, we used a generalized form of a recently reported parametrization based on the differential geometry and the thermodynamics of dispersed systems to ascertain the capability of decylpolyglucoside alone or in association with cholesterol to form vesicle structures (niosomes). The theoretical calculation of the energy balance involved in the vesicles formation was carried out using values of the critical concentration of formation (ccf), surface tension and the molar surface area of the non-ionic surfactant. Furthermore, in order to confirm the theoretical results found in this work, we prepared and characterized vesicles made with decylpolyglucoside and cholesterol. The vesicles were characterized using transmission electron microscopy and dynamic light scattering.