Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9741769 | Journal of Statistical Planning and Inference | 2005 | 8 Pages |
Abstract
We study an appropriate version of the score statistic to test the hypothesis of no linkage in a sample of phase known meioses and show that accurate approximations to the genome wide significance level can be obtained by using a large deviation approximation to evaluate Rice's formula for the expected number of upcrossings of a smooth random process.
Keywords
Related Topics
Physical Sciences and Engineering
Mathematics
Applied Mathematics
Authors
Jie Peng, D. Siegmund,