The maintenance of a PARAFAC calibration and the second-order property: application to the determination of ciprofloxacin in presence of enrofloxacin by excitation-emission fluorescence

The paper shows that the capability of detection of the fluorescence technique is satisfactory with respect to the legal regulation. The detection limits found for ciprofloxacin without and with interferent were 33 and 27 μg l−1 when the risks of false positive and false negative have been fixed at 5%. The corresponding hypothesis test has shown that there is neither a constant error nor a proportional error in the models constructed with PARAFAC, that is, the method can be considered accurate.