Microfluidic supported liquid membrane extraction

Miniature, microfluidic devices have been designed and fabricated for the enrichment of haloacetic acids in water. The analytical approach is based on supported liquid membrane (SLM) extraction followed by direct HPLC-UV detection without any derivatization. Channel dimensions and the flow rates affected enrichment factors and extraction efficiencies. Enrichment factors as high as 54 were obtained on a 2 cm × 2 cm extraction module. Large linearity ranges with good linearity, high precisions and detection limit as low as 2 ng/mL were obtained.