| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 975538 | Physica A: Statistical Mechanics and its Applications | 2014 | 4 Pages |
Abstract
The appearance of cancer in a tissue is thought to be the result of two or more successive mutations. We propose a stochastic model that allows for an exact computation of the distribution of the waiting time for a second mutation. This models the time of appearance of the first cancerous cell in a tissue. Our model is an alternative to the Moran model with mutations.
Related Topics
Physical Sciences and Engineering
Mathematics
Mathematical Physics
Authors
Rinaldo B. Schinazi,