Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9876371 | Radiation Physics and Chemistry | 2005 | 6 Pages |
Abstract
We discuss here modifications of DNA and protein radiolysis due to the interaction of these two partners in specific complexes. Experimental patterns of frank strand breaks (FSB) and alkali revealed breaks (ARB) obtained for DNA lac operator bound to the lac repressor and for a DNA containing an abasic site analog bound to the formamidopyrimidine-DNA glycosylase are reported. Experimental data are compared to predicted damage distribution obtained using the theoretical model RADACK.
Keywords
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Marie BÄgusová, Nathalie Gillard, Denise Sy, Bertrand Castaing, Michel Charlier, Melanie Spotheim-Maurizot,