Article ID Journal Published Year Pages File Type
9886604 Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 2005 14 Pages PDF
Abstract
Phosphatidylcholine is a prominent constituent of eukaryotic and some prokaryotic membranes. This Perspective focuses on the two enzymes that regulate its biosynthesis, choline kinase and CTP:phosphocholine cytidylyltransferase. These enzymes are discussed with respect to their molecular properties, isoforms, enzymatic activities, and structures, and the possible molecular mechanisms by which they participate in regulation of phosphatidylcholine levels in the cell.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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