Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9888148 | Clinica Chimica Acta | 2005 | 12 Pages |
Abstract
The primary goal of Laboratory Medicine is to provide information that is useful to assist medical decision-making and permits optimal health care. This type of information should be independently obtained of the measurement test kits and instruments, and also of the laboratory where the procedure is carried out. It is therefore important to achieve a level of comparability of laboratory results among the many measurement procedures available so that results are harmonized and interchangeable over space and time. The standardization of measurements is therefore of high priority. In recent years, numerous efforts have been made at the international level under the auspices of the IFCC and other organizations to standardize measurement results for many important analytes, e.g. enzymes, cardiac proteins, etc. The aim of this review is to discuss some concepts related to the achievement of standardization by the implementation of a metrologically correct measurement system, providing some examples on how these concepts can be applied in Laboratory Medicine.
Keywords
BIPMIFCCIVDcTnINISTalanine aminotrasferaseHbA1cIRMMGGTALTAACCJCTLMBCRInstitute for Reference Materials and Measurementsα-Amylaseγ-glutamyltransferaseASTAspartate aminotransferaseALPAlkaline phosphataseStandardizationAMYISOIn vitro diagnosticWorld Health OrganizationInternational Organization for StandardizationCertificationInternational Federation of Clinical Chemistry and Laboratory MedicineTraceabilitycardiac troponin Ilactate dehydrogenaseLDHmatrix assisted laser desorption/ionizationMALDIReference materialsNational Institute of Standards and TechnologyHemoglobin A1cCalibrationCreatine kinasehigh-pressure liquid chromatographyHPLCWHO
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Authors
M. Panteghini, J.C. Forest,