Article ID Journal Published Year Pages File Type
9889992 The International Journal of Biochemistry & Cell Biology 2005 11 Pages PDF
Abstract
In conclusion, both serine and tyrosine phosphorylation of STAT-3 are involved in the signaling pathway mediating the effects of cyclic strain on vascular SMC. Serine phosphorylation of STAT-3 is mediated by ERK1/2, while tyrosine phosphorylation is mediated by Src. A negative feedback loop was also found between p38 and ERK1/2.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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The role of STAT-3 in the mediation of smooth muscle cell response to cyclic strain
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