Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9890819 | International Journal of Biological Macromolecules | 2005 | 4 Pages |
Abstract
Previously we represented molecular model of collagen triple helix-DNA double helix complex [G.M. Mrevlishvili, D.V. Svintradze, Int. J. Macromol. 36 (2005) 324-326; G.M. Mrevlishvili, D.V. Svintradze, Int. J. Macromol. 35 (2005) 243-245]. We also proved that during the complex formation hydration of triple helix destroys and forms new water bridges maintaining the complex nano-structure. In this paper we demonstrate that small interfering RNA binds to atelocollagen directly to form siRNA-atelocollagen fiber complex.
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Biochemistry
Authors
David V. Svintradze, George M. Mrevlishvili,