| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9892150 | The Journal of Steroid Biochemistry and Molecular Biology | 2005 | 10 Pages |
Abstract
Our data altogether demonstrate that raloxifene has a potent inhibitory effect on IGF-I action, with a drastic effect on AP-1 triggered responses as well as on Akt phosphorylation, suggesting that it might be a useful therapeutic agent in tumors in which these signalling pathways become constitutively active.
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Authors
G. Freiss, F. Galtier, C. Puech, C. Aknin, T. Maudelonde, D. Chalbos, F. Vignon,