Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9894347 | Regulatory Peptides | 2005 | 8 Pages |
Abstract
The results of the study indicate that one mechanism through which N-terminal (1-34)PTHrP stimulates osteoclastic activity of sea bream scales, is through PTH1R and via the cAMP/AC intracellular signalling pathway. It appears, therefore, that fish scales can act as calcium stores and that (1-34)PTHrP regulates calcium mobilization from them; it remains to be established if this mechanism contributes to calcium homeostasis in vivo.
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Authors
J. Rotllant, B. Redruello, P.M. Guerreiro, H. Fernandes, A.V.M. Canario, D.M. Power,