Article ID Journal Published Year Pages File Type
9894347 Regulatory Peptides 2005 8 Pages PDF
Abstract
The results of the study indicate that one mechanism through which N-terminal (1-34)PTHrP stimulates osteoclastic activity of sea bream scales, is through PTH1R and via the cAMP/AC intracellular signalling pathway. It appears, therefore, that fish scales can act as calcium stores and that (1-34)PTHrP regulates calcium mobilization from them; it remains to be established if this mechanism contributes to calcium homeostasis in vivo.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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