Article ID Journal Published Year Pages File Type
9894361 Regulatory Peptides 2005 11 Pages PDF
Abstract
In summary, AZA and its metabolites exert no significant effect on intestinal epithelial restitution. However, they profoundly inhibit intestinal epithelial cell growth via various mechanisms: they cause a G2 cell cycle arrest in HT-29 cells, induce apoptosis in IEC-6 cells and dose-dependently inhibit intestinal epithelial proliferation.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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