Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9894361 | Regulatory Peptides | 2005 | 11 Pages |
Abstract
In summary, AZA and its metabolites exert no significant effect on intestinal epithelial restitution. However, they profoundly inhibit intestinal epithelial cell growth via various mechanisms: they cause a G2 cell cycle arrest in HT-29 cells, induce apoptosis in IEC-6 cells and dose-dependently inhibit intestinal epithelial proliferation.
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Authors
Sebastian Schroll, Alexander Sarlette, Katja Ahrens, Michael P. Manns, Michael Göke,