Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9894373 | Regulatory Peptides | 2005 | 7 Pages |
Abstract
The circulating ghrelin concentration is high in situations of nutritional deficiency (starvation) and low in situations of nutritional plenty (free access to food or TPN). The actual presence or absence of food in the GI tract seems irrelevant. Circulating insulin and glucose concentrations did not differ much between TPN rats and fed controls; serum lipids, however, were elevated in the TPN rats. We suggest that elevated blood lipid levels contribute to the suppression of circulating ghrelin in rats subjected to TPN for 8 days.
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Authors
Saleem S. Qader, Albert Salehi, Rolf HÃ¥kanson, Ingmar Lundquist, Mats Ekelund,