Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9894542 | Regulatory Peptides | 2005 | 6 Pages |
Abstract
The results suggest that, in obese Zucker rats, activation of the serotonergic system in the medial hypothalamus participates in IL-1β-induced anorexia. Since l-arginine, probably through NO stimulation, abolished both the anorexia and the serotonergic activation, it can be proposed that the NO system, either directly or indirectly, counteracts IL-1β anorexia. The hypothalamic serotonergic system is likely to mediate this NO effect.
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Authors
Anderson Iuras, Mônica Marques Telles, Clélia Rejane Antônio Bertoncini, Gui Mi Ko, Iracema Senna de Andrade, Vera Lúcia Flor Silveira, Eliane Beraldi Ribeiro,