| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9918589 | International Journal of Pharmaceutics | 2005 | 8 Pages |
Abstract
From the results obtained, NLC lipid organization guaranteed an increased indomethacin encapsulation in comparison with SLN. DSC static and dynamic measurements performed on SLN and NLC showed that oil nanocompartments incorporated into NLC solid matrix drastically influenced drug distribution inside the nanoparticle system. Controlled release from NLC system could be explained considering both drug partition between oil nanocompartments and solid lipid and a successive partition between solid lipid and water.
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Authors
Francesco Castelli, Carmelo Puglia, Maria Grazia Sarpietro, Luisa Rizza, Francesco Bonina,