Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9918645 | International Journal of Pharmaceutics | 2005 | 9 Pages |
Abstract
The glucoside and mannoside derivatives of the NSAIDs flurbiprofen, ibuprofen, ketoprofen and naproxen were synthesised and their penetration through human skin was determined. Experimental transdermal flux data showed that the parent NSAIDs penetrated human skin to a much higher extent than the glycosides.
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Authors
Henk Swart, Jaco C. Breytenbach, Jonathan Hadgraft, Jeanetta du Plessis,