Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9918715 | International Journal of Pharmaceutics | 2005 | 5 Pages |
Abstract
Potential approaches to achieve cytosolic delivery of liposomal macromolecules are presented. These approaches include: (1) the co-encapsulation of fusogenic peptides into targeted drug-containing liposomes (2) coupling of the HIV-1-derived cell-penetrating peptide TAT to the surface of liposomes and (3) photochemical internalization, based on photochemically inducible permeabilization of endocytic vesicles.
Keywords
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Authors
Marjan M. Fretz, Enrico Mastrobattista, Gerben A. Koning, Wim Jiskoot, Gert Storm,