Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9918930 | International Journal of Pharmaceutics | 2005 | 8 Pages |
Abstract
The drug release profiles of rehydrated liposomes followed Higuchi's square root model. Also, the obtained release profiles were all biphasic: a rapid initial drug release phase (burst release of the portion of the drug that leaked out of liposomes during the lyophilization) was followed by a slower, approximately constant drug release phase (zero-order kinetics).
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Authors
M. Glavas-Dodov, E. Fredro-Kumbaradzi, K. Goracinova, M. Simonoska, S. Calis, S. Trajkovic-Jolevska, A.A. Hincal,