| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9940835 | American Journal of Hypertension | 2005 | 7 Pages |
Abstract
Histopathologic and biochemical findings indicate that, in the DS rat, salt-induced hypertensive nephropathy is associated with increased oxidative stress. Superoxide mimetic tempol can reduce this detrimental effect of salt feeding through TGF-β1 suppression and consequently prevent the development of hypertension and hypertensive nephropathy.
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Authors
Ryohei Hisaki, Hirotaka Fujita, Fumio Saito, Toshio Kushiro,