Article ID Journal Published Year Pages File Type
9941035 American Journal of Hypertension 2005 7 Pages PDF
Abstract
Basal and Ang II-induced NAD(P)H-driven ROS generation are enhanced in VSMCs from SHR during development of hypertension, but not in cells from prehypertensive rats. Transactivation of IGF-1R by Ang II may be important in vascular oxidative excess in the development of hypertension in SHR.
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Health Sciences Medicine and Dentistry Cardiology and Cardiovascular Medicine
Preview
Vascular smooth muscle cell NAD(P)H oxidase activity during the development of hypertension: Effect of angiotensin II and role of insulinlike growth factor-1 receptor transactivation
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