Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9953834 | Magnetic Resonance Imaging | 2018 | 46 Pages |
Abstract
Diffusion-magnetic resonance elastography (dMRE) is an emerging practical technique that can acquire diffusion magnetic resonance imaging and MRE simultaneously. However, a signal loss attributable to intravoxel phase dispersion (IVPD) interferes with the calculation of the apparent diffusion coefficient (ADC). This study presents an approach to dMRE that reduces the influence of IVPD by introducing a new pulse sequence. The existing and proposed techniques were performed using a phantom comprising five rods with different elasticities at 60â¯Hz vibration to investigate the accuracy of previous and proposed dMRE techniques. The measures of ADC and stiffness, obtained by using both dMRE techniques, were compared with conventional spin-echo (SE) diffusion and SE-MRE. Then, we evaluated those differences by using the mean of absolute differences (MAD) in each rod within the phantom. The results of the MAD of the stiffness from both dMRE techniques showed almost no difference. In contrast, the value of the ADC MAD (MADâ¯ââ¯0.16â¯Ãâ¯10â3â¯mm2/s), obtained in the soft region within the phantom with the previous dMRE technique, was large. This value was about 2.7 times that of the value produced by the proposed dMRE technique. This difference must reflect the degree of influence of IVPD in both techniques. These results demonstrate that our dMRE technique is a robust method for addressing the signal loss attributable to IVPD.
Keywords
SNRLFEQSIPNRMREmpMRIDTIMADIVPDDSGROIADCMSGDFTMulti-parametric MRIQuantitative MRISpin echoMRIstandard deviationMagnetic resonance elastographyAlzheimer's diseaseDiscrete Fourier transformationQ-space imagingdiffusion tensor imagingMagnetic resonance imagingStiffnessapparent diffusion coefficientshear modulusregion of interestSignal-to-noise ratioHARDIDiffusion
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Condensed Matter Physics
Authors
Daiki Ito, Tomokazu Numano, Kazuyuki Mizuhara, Toshikatsu Washio, Masaki Misawa, Naotaka Nitta,