| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9954101 | Clinica Chimica Acta | 2018 | 9 Pages |
Abstract
Serum samples provide higher sensitivity for biomarker discovery studies. Due to the presence of spurious amount of sarcosine in vacutainer EDTA tubes, plasma EDTA is not suitable for studies requiring accurate quantification of sarcosine.
Keywords
ADMASOPssDMALC-MSUHPLCFIAC18:1PCAfirst principal componentFlow-injection analysisPrincipal component analysissymmetric dimethylarginineasymmetric dimethylarginineStandard operating proceduresSarcosineSerumLiquid chromatography mass spectrometryTargeted metabolomicssecond principal componentHILICPc 4Ultra-high performance liquid chromatographyhydrophilic interaction liquid chromatographyquality control
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Authors
Giuseppe Paglia, Fabiola M. Del Greco, Baldur B. Sigurdsson, Johannes Rainer, Chiara Volani, Andrew A. Hicks, Peter P. Pramstaller, Sigurdur V. Smarason,