Hemodynamic effects of short-term infusion of a vasopressin V1A/V2 receptor antagonist conivaptan in patients withchronic heart failure during submaximal exercise

Heart failure is associated with a reduced exercise capacity. Our aim was to investigate if infusion with a V1A/V2-receptor antagonist, conivaptan, leads to an increase in cardiac output at a constant or reduced filling pressure (pulmonary capillary wedge pressure) during submaximal exercise.