Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9959489 | Journal of the American College of Cardiology | 2005 | 7 Pages |
Abstract
Elderly patients with a V592fs/8 mutation in the MyBPC gene may evolve into the “end-stage” HCM, characterized by left ventricular systolic dysfunction, cavity dilation, and irreversible heart failure. The clinical course in patients with this mutation is not benign in the long run, with progressive left ventricular remodeling with advancing age.
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Authors
Toru MD, Hiroaki MD, PhD, Makoto MD, Yoshihisa MD, PhD, Nobuhiko MD, Naohito MD, Takashi MD, Jun MD, PhD, Masanori MD, PhD, Akinori MD, PhD, Yoshinori L. (FACC),