| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9959664 | Journal of the American College of Cardiology | 2005 | 12 Pages |
Abstract
A hypoxia-regulated HO-1 vector modification of MSCs enhances the tolerance of engrafted MSCs to hypoxia-reoxygen injury in vitro and improves their viability in ischemic hearts. This demonstration is the first showing that a physiologically inducible vector expressing of HO-1 genes improves the survival of stem cells in myocardial ischemia.
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Authors
Yao Liang MD, PhD, Yi MD, PhD, Y. Clare PhD, Keping PhD, Leping MS, M. Ian PhD, DSc,