| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9959824 | Journal of the American College of Cardiology | 2005 | 8 Pages |
Abstract
Chronic CHD in diabetic patients is characterized by an increased VEGF myocardial expression and a decreased expression of its receptors along with a down-regulation of its signal transduction. The latter could be partially responsible for the reduced neoangiogenesis in diabetic patients with ischemic cardiomyopathy.
Keywords
eNOSphospho-eNOsCHDPI3KRT-PCRmRNAMyocardial infarctionright ventricle/ventricularleft ventricle/ventricularcoronary heart diseasecardiovascular diseaseCVDmessenger ribonucleic acidEndothelial cellendothelial nitric oxide synthaseVascular endothelial growth factorVascular Endothelial Growth Factor (VEGF)phosphatidylinositol-3 kinaseReverse transcriptase-polymerase chain reactionoptical density
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Authors
Ferdinando Carlo MD, PhD, Daniele MD, Ornella MD, Georgina M. PhD, Michele MD, Michelangelo MD, Claudio MD, Rodolfo MD, Raffaele MD, PhD, Domenico MD, Ciro MD, Maurizio MD, Roberto MD, Teresa MD,