| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10212425 | Infection, Genetics and Evolution | 2018 | 32 Pages |
Abstract
Our results underline the importance of the functional SOCS3 polymorphisms in the modulation of CHC progression and suggest their contribution to HCC development by affecting its mRNA expression and perturbing key metabolic parameters.
Keywords
ADLDMCHCCHCSOCS-3PBMCsT2DSOCS3MLDALTMENASNPsPI3KHCCHCV infectionASTAspartate aminotransferaseAlanine aminotransferaseinterferonIFNmRNA expressionType 2 diabetesperipheral blood mononuclear cellsconfidence intervalsPhosphatidylinositol 3-kinaseInsulin resistanceodds ratiochronic hepatitis CHepatitis C virusHCVPolymorphismSingle nucleotide polymorphismsHepatocellular carcinoma
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Authors
Fatima Zahra Jadid, Hajar Chihab, Hanane Salih Alj, Raouia Elfihry, Imane Zaidane, Sanaa Tazi, Wafaa Badre, Agnes Marchio, Kamal Marhoum El Filali, Mohammed Tahiri, Rachid Saile, Pascal Pineau, Sayeh Ezzikouri, Soumaya Benjelloun,