Discovery of novel 2-(alkylmorpholin-4-yl)-6-(3-fluoropyridin-4-yl)-pyrimidin-4(3H)-ones as orally-active GSK-3Î² inhibitors for Alzheimer's disease

Article ID	Journal	Published Year	Pages	File Type
10585681	Bioorganic & Medicinal Chemistry Letters	2015	6 Pages	PDF

Keywords

Alzheimer’s disease Glycogen synthase kinase 3β

Related Topics

Physical Sciences and Engineering Chemistry Organic Chemistry

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Discovery of novel 2-(alkylmorpholin-4-yl)-6-(3-fluoropyridin-4-yl)-pyrimidin-4(3H)-ones as orally-active GSK-3Î² inhibitors for Alzheimer's disease

Authors

Kenji Fukunaga, Daiki Sakai, Kazutoshi Watanabe, Kazuki Nakayama, Toshiyuki Kohara, Hiroshi Tanaka, Shinji Sunada, Mika Nabeno, Masako Okamoto, Ken-Ichi Saito, Jun-ichi Eguchi, Akiko Mori, Shinji Tanaka, Keiko Inazawa, Takashi Horikawa,