| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10586970 | Bioorganic & Medicinal Chemistry Letters | 2014 | 10 Pages |
Abstract
A C4 derivative of 1,1-dimethyl-furo[3,4-c]pyridine-3-one (compound 10) and a thieno[2,3-d]pyrimidine-4-one (compound 40) have been identified as β1c (10) and β2c or β2i (40) site-specific inhibitors of 20S proteasomes.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
![New C4- and C1-derivatives of furo[3,4-c]pyridine-3-ones and related compounds: Evidence for site-specific inhibition of the constitutive proteasome and its immunoisoform](/preview/png/10586970.png "First Page Preview: New C4- and C1-derivatives of furo[3,4-c]pyridine-3-ones and related compounds: Evidence for site-specific inhibition of the constitutive proteasome and its immunoisoform")
Authors
Anna Hovhannisyan, The Hien Pham, Dominique Bouvier, Alexander Piroyan, Laure Dufau, Lixian Qin, Yan Cheng, Gagik Melikyan, Michèle Reboud-Ravaux, Michelle Bouvier-Durand,