Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10587068 | Bioorganic & Medicinal Chemistry Letters | 2014 | 4 Pages |
Abstract
A series of seven pleuromutilin derivatives were studied by chemical footprinting for the binding to Escherichia coli ribosomes and for their ability to inhibit the growth of two Staphylococcus aureus strains. One compound shows an excellent effect similar to the known drug valnemulin.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ida Dreier, Lykke H. Hansen, Poul Nielsen, Birte Vester,