| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10587616 | Bioorganic & Medicinal Chemistry Letters | 2013 | 5 Pages |
Abstract
A series of N-glucosides was synthesized for biological evaluation as human hSGLT2 inhibitors. Compound 9d possessing an indole core structure showed good in vitro activity and favorable in vivo potency with regard to urinary glucose excretion (UGE) in rats.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yasuo Yamamoto, Eiji Kawanishi, Yuichi Koga, Shigeki Sakamaki, Toshiaki Sakamoto, Kiichiro Ueta, Yasuaki Matsushita, Chiaki Kuriyama, Minoru Tsuda-Tsukimoto, Sumihiro Nomura,