Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10587638 | Bioorganic & Medicinal Chemistry Letters | 2013 | 5 Pages |
Abstract
A novel series of imidazole derivatives were identified to be potent CGRP antagonists. Extensive SAR of the imidazole ring is presented leading to the discovery compound 43.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
George Tora, Andrew P. Degnan, Charles M. Conway, Walter A. Kostich, Carl D. Davis, Sokhom S. Pin, Richard Schartman, Cen Xu, Kimberly A. Widmann, John E. Macor, Gene M. Dubowchik,