Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10587715 | Bioorganic & Medicinal Chemistry Letters | 2013 | 4 Pages |
Abstract
A series of pyrazinones were prepared and evaluated as potential CRF1R PET imaging agents. Optimization of their CRF1R binding potencies and octanol-phosphate buffer phase distribution coefficients is discussed herein.
Related Topics
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Authors
Derek J. Denhart, Dmitry Zuev, Jonathan L. Ditta, Richard A. Hartz, Vijay T. Ahuja, Ronald J. Mattson, Hong Huang, Gail K. Mattson, Larisa Zueva, Julia M. Nielsen, Edward S. Kozlowski, Nicholas J. Lodge, Joanne J. Bronson, John E. Macor,