| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10587715 | Bioorganic & Medicinal Chemistry Letters | 2013 | 4 Pages |
Abstract
A series of pyrazinones were prepared and evaluated as potential CRF1R PET imaging agents. Optimization of their CRF1R binding potencies and octanol-phosphate buffer phase distribution coefficients is discussed herein.
Related Topics
Physical Sciences and Engineering
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Organic Chemistry
Authors
Derek J. Denhart, Dmitry Zuev, Jonathan L. Ditta, Richard A. Hartz, Vijay T. Ahuja, Ronald J. Mattson, Hong Huang, Gail K. Mattson, Larisa Zueva, Julia M. Nielsen, Edward S. Kozlowski, Nicholas J. Lodge, Joanne J. Bronson, John E. Macor,