Article ID Journal Published Year Pages File Type
10587894 Bioorganic & Medicinal Chemistry Letters 2013 5 Pages PDF
Abstract
A series of highly potent & selective adamantane derived CB2 agonists was identified in a high-throughput screen. A SAR was established and physicochemical properties were significantly improved. This was accompanied by potency of the compounds on the Q63R variant and varying β-arrestin data which will support the insight into their relevance for the in vivo situation.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Authors
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