Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10587941 | Bioorganic & Medicinal Chemistry Letters | 2013 | 4 Pages |
Abstract
Two fan-shaped bile acid trimers have been synthesized via CuI-catalyzed azide-alkyne cycloaddition (CuAAC) 'click chemistry', and their extraction experiments of cresol red sodium (CR) and pyrene were investigated in the polar and non-polar solvents, respectively. The transmission electron microscopy (TEM) results showed that the homogenous hollow capsules formed with the diameter size range of 40-70Â nm in a solution of water and acetone. Thus the amphiphilicity of fan-shaped bile acid trimers might be used as the promising candidate in biological and drug delivery applications.
Keywords
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jinrong Lu, Chulong Liu, Jun Hu, Yong Ju,