Article ID Journal Published Year Pages File Type
10587941 Bioorganic & Medicinal Chemistry Letters 2013 4 Pages PDF
Abstract
Two fan-shaped bile acid trimers have been synthesized via CuI-catalyzed azide-alkyne cycloaddition (CuAAC) 'click chemistry', and their extraction experiments of cresol red sodium (CR) and pyrene were investigated in the polar and non-polar solvents, respectively. The transmission electron microscopy (TEM) results showed that the homogenous hollow capsules formed with the diameter size range of 40-70 nm in a solution of water and acetone. Thus the amphiphilicity of fan-shaped bile acid trimers might be used as the promising candidate in biological and drug delivery applications.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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