| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10587956 | Bioorganic & Medicinal Chemistry Letters | 2013 | 4 Pages |
Abstract
A microwave-assisted, one-pot, coupling reaction for the synthesis of C5-alkynyl-uracil and cytosine glucopyranonucleosides has been developed. Among them, 5-phenylethynyluracil pyranonucleoside derivative 6a, effectively inhibited tumor cell proliferation (IC50 of 5.2-6.2 μM).
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Authors
Athina Dimopoulou, Stella Manta, Christos Kiritsis, Dimitra-Niki Gkaragkouni, Ioannis Papasotiriou, Jan Balzarini, Dimitri Komiotis,