| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10587976 | Bioorganic & Medicinal Chemistry Letters | 2013 | 4 Pages |
Abstract
Five new phenolic glycosides, hedyotosides A-E (1-5), including a new cyanogenic glycoside (1), along with 10 known compounds (6-15) were isolated from the whole plants of Hedyotis scandens. The structures of compounds 1-5 were established by extensive spectroscopic analyses and acid hydrolysis. All the isolated compounds were evaluated for their in vitro antiviral activity against respiratory syncytial virus (RSV) with cytopathic effect (CPE) reduction assay. Compounds 6 and 15 showed anti-RSV effects with IC50 values of 20 and 25 μg/mL, respectively.
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Authors
Guo-Cai Wang, Tao Li, Fang-Ye Deng, Yao-Lan Li, Wen-Cai Ye,