Article ID Journal Published Year Pages File Type
10587995 Bioorganic & Medicinal Chemistry Letters 2013 4 Pages PDF
Abstract
A series of 21 new amino alcohol fused spirochromone conjugates have been synthesized, characterized with analytical data and evaluated their antimycobacterial activity against Mycobacterium tuberculosis (virulent strain H37Rv) in vitro. Some of the compounds exerted significant inhibition, in particular, compound 4f found to be the most potent derivative exhibiting MIC = 3.13 μg/mL.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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