| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10588000 | Bioorganic & Medicinal Chemistry Letters | 2013 | 4 Pages |
Abstract
The readily available 3H-1,2,4-dithiazol-3-one molecule compound 4n was shown to be potent against the virulent Mycobacterium tuberculosis H37Rv strain by a microdilution method, demonstrating a better safety profile on human normal liver L02 cells than the lead compound HT1171, which was reported as a potent proteasome inhibitor of Mycobacterium bovis var. bacilli Calmette-Guérin (BCG).
Keywords
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jianzhong Yang, Weiyi Pi, Li Xiong, Wei Ang, Tao Yang, Jun He, Yuanyuan Liu, Ying Chang, Weiwei Ye, Zhenling Wang, Youfu Luo, Yuquan Wei,