Article ID Journal Published Year Pages File Type
10588026 Bioorganic & Medicinal Chemistry Letters 2013 4 Pages PDF
Abstract
Pyrolidine ring in the N-acylphenylalanine class of VLA-4 antagonists has been successfully replaced by a 4,5-dihydro-5-methylisoxazoline and resulting derivative (14p) found to be potent in the series and also found to be metabolically stable in vitro.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Authors
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