| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10588235 | Bioorganic & Medicinal Chemistry Letters | 2012 | 4 Pages |
Abstract
The design, synthesis, and SAR for a series of aminothiazole pyrimidines as potent LIMK inhibitors are described. Compound 31 effectively inhibited cofilin phosphorylation in cells in a dose dependent manner.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Liqi He, Steven P. Seitz, George L. Trainor, David Tortolani, Wayne Vaccaro, Michael Poss, Christine M. Tarby, John S. Tokarski, Becky Penhallow, Chen-Yi Hung, Ricardo Attar, Tai-An Lin,