| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10588306 | Bioorganic & Medicinal Chemistry Letters | 2012 | 4 Pages |
Abstract
1-(5-Chloro-2-methyl-phenyl)-3-[4-(5-trifluoromethyl-pyrazol-1-yl)-phenyl]-thiourea (AW00178) mediated sensitization to TRAIL-mediated apoptosis in H1299 cells by increasing sensitivity and decreasing resistance to TRAIL via the induction of c-Jun-dependent CHOP expression and the reduction of Akt-dependent survivin expression, respectively.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Byung Jun Ryu, Mi-Kyung Hwang, Mikyung Park, Kyunghee Lee, Seong Hwan Kim,