| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10588334 | Bioorganic & Medicinal Chemistry Letters | 2012 | 4 Pages |
Abstract
A series of spacer-varied biotinylated PSMA inhibitors were synthesized and evaluated, which exhibited spacer length-dependent effects on inhibitory potency, mode of inhibition. Moreover, only one of them can be used to form a complex with Cy5-streptavidin for fluorescence imaging of prostate cancer cells.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Tiancheng Liu, Jessie R. Nedrow-Byers, Mark R. Hopkins, Lisa Y. Wu, Jeonghoon Lee, Peter T.A. Reilly, Clifford E. Berkman,